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SLE in the 21st Century: Breakthroughs, Burdens, and Bright Horizons

Objectives:

To highlight key milestones and innovations that have transformed lupus care over the past decades
To review and evaluate current standard-of-care practices in SLE management
To explore emerging scientific developments and novel therapeutic approaches in SLE

Agenda:


13:40-13:45	Welcome and Introduction Shingo Nakayamada
13:45-13:55	Lupus Care: Progress and Innovation Masayoshi Harigai Epidemiology of lupus: global and Asia–Pacific perspectives Therapeutic challenges and the shift from symptom-driven to disease-modifying approaches Improved patient outcomes, including reduced organ damage and enhanced survival
13:55-14:20	Optimizing Current SLE Management Sandra Navarra Overview of current diagnostic and management guidelines Approved standard-of-care therapies: corticosteroids, immunosuppressants, and biologics Best practices in glucocorticoid tapering and minimizing long-term toxicity Managing lupus nephritis and other organ-specific complications Multidisciplinary and patient-centred care Unmet needs
14:20-14:45	Future Horizons in Lupus Eric Morand Emerging insights into lupus pathophysiology: novel targets and mechanisms of action Potential of advanced biologics and immune-targeted strategies: immunomodulation vs immunosuppression Promising developments in cellular therapies: CAR-T and related technologies Advances in precision medicine: tailored treatments guided by biomarkers Implications of novel therapies on long-term patient outcomes and remission
14:45-15:05	Q&A All
15:05-15:10	Close Shingo Nakayamada

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